You could sense the tension at Levi’s Stadium Sunday the moment rookie Isaac Guerendo fumbled the second half kickoff and the ...

The Patriots’ Week 4 loss was on the offense, but the blowout was on a defense once expected to perform as an elite unit.

San Francisco 49ers quarterback Brock Purdy fires a deep ball and finds wide receiver Deebo Samuel for a 53-yard gain against the New England Patriots.

The San Francisco 49ers are back to .500, but there is still plenty of criticism directed at star wide receiver Brandon Aiyuk ...

San Francisco 49ers QB Brock Purdy maintained his focus downfield for a 53-yard completion to WR Deebo Samuel Sr. in the team ...

Kyle Shanahan will have to figure out a contingency plan after the San Francisco 49ers lost another starter to injury on ...

The Patriots are looking to snap a 2-game losing streak and avoid a devastating 1-3 hole as they take on a 49ers squad ...

The 49ers, who haven't had much positive injury news this year, officially will have two of their best offensive players ...

Samuel (calf) finished with three receptions (five targets) for 58 yards and 14 rushing yards on two attempts in Sunday's 30-13 win over the Patriots.

San Francisco 49ers wide receiver Deebo Samuel is active for Sunday's game against the New England Patriots. Samuel missed ...

The 49ers aim to reverse a disappointing start to the season Sunday afternoon when they host the New England Patriots at Levi ...