San Francisco 49ers quarterback Brock Purdy made NFL history following the team's win over the Patriots on Sunday.

San Francisco 49ers tight end George Kittle received high praise from Vernon Davis. The former NFL player believes he sees much of himself in Kittle.

The San Francisco 49ers had a dominant 30-13 victory over the New England Patriots on Sunday, improving to 2-2 on the season ...

Looking at Sunday’s Arizona Cardinals at San Francisco 49ers Week 5 NFL odds, lines and trends. Here’s what you need to know.

Rashee Rice and Anthony Richardson were among the NFL players injured in Week 4. Those hurt in Thursday and Sunday games will be evaluated for their injuries this week to determine timelines for ...

Fred Warner returned an interception for a score and the San Francisco 49ers snapped a two-game skid by beating the New ...

Jayden Daniels is off to a generational start to his career. He has easily the league’s highest completion percentage and the ...

The Oct. 6 matchup between the Green Bay Packers (2-2) and Los Angeles Rams (1-3) features a standoff at the QB position, ...

Stafford completed 20 of 29 passes for 224 yards. But his late interception on first down at the Los Angeles 8 ended any potential comeback. Tutu Atwell had 82 yards receiving with Cooper Kupp (ankle) ...

The 49ers rebounded from back-to-back road losses by racing to a 20-0 lead Sunday and holding on to beat the New England ...

With just over four minutes left in Sunday's game against the Los Angeles Rams, the San Francisco 49ers offense snapped the ...

Reeling from a last-minute loss to the Rams, the 49ers needed a game to find themselves. New England served as a necessary sparring partner for the Niners in a ...