Frank Ragnow, Derrick Barnes, Marcus Davenport are out, and Brian Branch (doubtful) is unlikely to play. That will lead to some serious changes for the Lions on Monday night.

Detroit Lions head coach Dan Campbell provided an injury update on Marcus Davenport, Brian Branch, Alim McNeill, Sam LaPorta and Derrick Barnes.

It’s a big loss for the defense, which was relying on Barnes to play a variety of roles, from edge rusher to run-stuffer to occasional cover man in the slot.

Lions head coach Dan Campbell on Monday confirmed LaPorta was day-to-day after reports surfaced that it's a low-ankle sprain for the tight end.

The Lions’ injury situation just keeps getting worse, with linebacker Derrick Barnes expected to be placed on injured reserve after sustaining a knee injury in Detroit’s Week 3 victory over the Cardinals on Sunday, per ESPN’s Jeremy Fowler.

The Lions signed WR Tim Patrick from the practice squad to the 53-man roster and still have one open roster spot.

Defensive end Marcus Davenport and linebacker Derrick Barnes were both placed on IR Tuesday after suffering significant injuries in Detroit’s Week 3 triumph over the Arizona Cardinals. Davenport’s injury was reported as torn triceps, while Barnes suffered a knee injury.

The Lions announced four roster moves on Tuesday, including officially placing DE Marcus Davenport and LB Derrick Barnes on injured reserve. The team also signed WR Tim Patrick to their active roster and signed DB Morice Norris to the practice squad.